Hubert Hondermarck Selected Research

sortilin

4/2022	Expression of NGF/proNGF and Their Receptors TrkA, p75NTR and Sortilin in Melanoma.
7/2020	Nerve growth factor and its receptor tyrosine kinase TrkA are overexpressed in cervical squamous cell carcinoma.
1/2020	The Membrane Protein Sortilin Can Be Targeted to Inhibit Pancreatic Cancer Cell Invasion.
1/2018	Neurotrophin Receptors TrkA, p75NTR, and Sortilin Are Increased and Targetable in Thyroid Cancer.
1/2018	The neurotrophic tyrosine kinase receptor TrkA and its ligand NGF are increased in squamous cell carcinomas of the lung.
4/2015	Sortilin is associated with breast cancer aggressiveness and contributes to tumor cell adhesion and invasion.
1/2012	Pro-nerve growth factor induces autocrine stimulation of breast cancer cell invasion through tropomyosin-related kinase A (TrkA) and sortilin protein.

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Hubert Hondermarck Research Topics

Disease

46	Neoplasms (Cancer) 04/2022 - 08/2002
37	Breast Neoplasms (Breast Cancer) 06/2022 - 02/2002
11	Neoplasm Metastasis (Metastasis) 04/2022 - 10/2002
7	Prostatic Neoplasms (Prostate Cancer) 11/2021 - 12/2014
4	Pancreatic Neoplasms (Pancreatic Cancer) 01/2022 - 01/2020
4	Cancer Pain 01/2020 - 12/2012
4	Thyroid Neoplasms (Thyroid Cancer) 11/2019 - 05/2016
4	Carcinogenesis 12/2017 - 11/2007
3	Adenocarcinoma 01/2020 - 05/2002
2	Lymphatic Metastasis 04/2022 - 11/2019
2	Melanoma (Melanoma, Malignant) 04/2022 - 11/2015
2	Brain Neoplasms (Brain Tumor) 01/2022 - 09/2015
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 07/2020 - 01/2018
2	Pain (Aches) 01/2020 - 01/2018
2	Triple Negative Breast Neoplasms 01/2019 - 01/2015
1	Nevi and Melanomas 04/2022
1	Nevus (Nevi) 04/2022
1	Neurofibrosarcoma (MPNST) 01/2022
1	Esophageal Squamous Cell Carcinoma 06/2021
1	Shwachman-Diamond Syndrome 12/2020
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 07/2020
1	Virus Diseases (Viral Diseases) 05/2020
1	COVID-19 05/2020
1	Esophageal Neoplasms (Esophageal Cancer) 01/2020
1	Male Infertility (Male Sterility) 01/2020
1	Papillary Thyroid Cancer 01/2020
1	Pathologic Processes 01/2020
1	follicular Thyroid cancer 01/2020
1	Diffuse Intrinsic Pontine Glioma 11/2019
1	Glioma (Gliomas) 11/2019
1	Tertiary Lymphoid Structures 01/2019

Drug/Important Bio-Agent (IBA)

31	Proteins (Proteins, Gene)FDA Link 06/2022 - 02/2002
23	Nerve Growth Factor (NGF)IBA 04/2022 - 05/2003
13	Biomarkers (Surrogate Marker)IBA 01/2022 - 03/2007
9	Nerve Growth Factors (Neurotrophins)IBA 11/2021 - 08/2003
8	Small Interfering RNA (siRNA)IBA 01/2020 - 01/2007
7	sortilinIBA 04/2022 - 01/2012
7	Nerve Growth Factor Receptors (Neurotrophin Receptors)IBA 04/2022 - 05/2003
7	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 04/2022 - 04/2011
7	ProteomeIBA 01/2022 - 04/2008
7	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 11/2021 - 12/2012
6	Phosphotransferases (Kinase)IBA 01/2022 - 04/2011
6	Messenger RNA (mRNA)IBA 01/2020 - 08/2002
5	Biological ProductsIBA 01/2022 - 05/2003
4	Pharmaceutical PreparationsIBA 01/2022 - 09/2004
4	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2022 - 04/2011
4	Blocking AntibodiesIBA 01/2020 - 04/2011
4	Neurotransmitter Agents (Neurotransmitter)IBA 01/2019 - 05/2015
4	Nerve Growth Factor Receptor (Nerve Growth Factor Receptor, Low Affinity)IBA 04/2011 - 08/2003
4	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 08/2005 - 08/2002
3	AntibodiesIBA 06/2022 - 01/2008
3	ErbB Receptors (EGF Receptor)IBA 01/2022 - 01/2009
3	neurotrophin 4IBA 11/2021 - 04/2011
3	Membrane Proteins (Integral Membrane Proteins)IBA 01/2020 - 04/2015
2	GAP-43 Protein (GAP 43 Protein)IBA 06/2022 - 01/2021
2	Fluorouracil (Carac)FDA LinkGeneric 01/2022 - 08/2005
2	Tyrosine Kinase InhibitorsIBA 07/2020 - 01/2020
2	Adrenergic Agents (Adrenergic Drugs)IBA 01/2020 - 01/2018
2	tyrosine receptor (receptor, tyrosine)IBA 11/2019 - 01/2018
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2019 - 01/2018
2	LigandsIBA 01/2018 - 01/2016
2	AlbuminsIBA 05/2017 - 12/2016
2	TropomyosinIBA 05/2017 - 01/2012
2	Cadherins (E-Cadherin)IBA 02/2017 - 01/2005
2	Peptides (Polypeptides)IBA 01/2016 - 01/2005
2	Conditioned Culture MediaIBA 01/2012 - 07/2007
2	matrigelIBA 06/2010 - 01/2005
2	H19 long non-coding RNAIBA 08/2005 - 05/2002
2	Molecular Chaperones (Chaperone, Molecular)IBA 10/2002 - 08/2002
1	Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA 06/2022
1	ParaffinIBA 06/2022
1	Formaldehyde (Formol)FDA Link 06/2022
1	Interferon Type IIBA 01/2022
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 01/2022
1	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2022
1	X-Box Binding Protein 1IBA 01/2022
1	Transcription Factors (Transcription Factor)IBA 01/2022
1	EnzymesIBA 11/2021
1	ImmunosorbentsIBA 11/2021
1	Protein Phosphatase 2 (Protein Phosphatase 2A)IBA 12/2020
1	AndrogensIBA 08/2020
1	Growth Factor ReceptorsIBA 05/2020
1	Cholinergic Agents (Cholinergics)IBA 01/2020
1	Carrier Proteins (Binding Protein)IBA 01/2020
1	Trastuzumab (Herceptin)FDA Link 01/2020
1	AF38469IBA 01/2020
1	RacivirIBA 01/2020
1	activin AIBA 11/2019
1	Lysine (L-Lysine)FDA Link 11/2019
1	Amino Acids FDA Link 11/2019
1	SugarsIBA 11/2019
1	Methionine (L-Methionine)FDA Link 11/2019
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 11/2019
1	dipinacoline glutamateIBA 11/2019
1	Edetic Acid (EDTA)FDA Link 01/2018
1	PeriostinIBA 01/2018

Therapy/Procedure

15	Therapeutics 04/2022 - 06/2010
3	Denervation 01/2020 - 01/2017
1	Castration 08/2020
1	Radiotherapy 08/2020